Polynucleotides are an injectable bio-stimulating treatment that we offer at Revitalise Skincare Clinic. Treatment is the perfect solution for individuals who are looking to achieve a more youthful complexion. They are designed to improve skin quality, elasticity and appearance. If you’re wondering ‘how long does polynucleotides treatment last’ and other frequently asked questions, read on to find out.
What are Polynucleotides?
Polynucleotides are a long chain of nucleotides, nucleotides are the building blocks of DNA crucial for cellular repair and regeneration. They derive from purified fish DNA, typically from salmon or trout. Polynucleotides are a revolutionary anti-ageing treatment that promote deep skin renewal and collagen production for long lasting rejuvenation.
As we age, collagen production declines, which is why our skin can sag and become more wrinkled. When we inject Polynucleotides into the skin they reach the cells called fibroblasts. Fibroblasts are responsible for the formation of collagen production, which helps maintain the skins firm structure. Polynucleotides stimulate the body’s cells to help produce the collagen that we lose from ageing.
How long does Polynucleotides treatment last?
Initial results are typically seen three weeks after treatment. For optimal results we recommend a course of treatment which consists of three sessions three weeks apart. Treatment typically will last from six to nine months. After your course of treatment, we often recommend having treatments six monthly to maintain results.
Following treatment you can expect your skin to be firmer, smoother and more radiant. You’ll notice a more even skin tone that looks more youthful. Polynucleotides continue to work in the skin for the first 12 weeks after treatment so results continue to improve over time.
Can Polynucleotides be used alongside other treatments?
At Revitalise Skincare Clinic we offer Plinest TM. Plinest TM is known as a skin primer, meaning it can prepare the skin and make it more receptive to other treatments such as dermal fillers, chemical peels and microneedling. If used afterwards, Plinest TM can enhance results and keep the skin looking good for longer.
What are the benefits of Polynucleotides?
Polynucleotides are an innovative approach to skin regeneration, they offer so many amazing benefits to the skin which include:
- Promotes collagen and elastin production – By boosting collagen and elastin production, treatment enhances the skins firmness which helps with the appearance of sagging.
- Improves the skins texture – Polynucleotides can help smooth and even out the skins surface, making them a great treatment option for individuals who struggle with acne scarring and texture.
- Reduces the appearance of fine lines and wrinkles – The regenerative properties of polynucleotides help smooth out fine lines and wrinkles, giving the skin a more youthful appearance.
- Enhances skin hydration – They exhibit hydrating properties and improve the skins ability to retain water. This promotes healthier and more supple skin.
- Skin brightening effects – This includes darkness from under eye circles.
- Anti-inflammatory effects – Polynucleotides have natural anti-inflammatory properties, making them effective at evening out the skin tone and reducing redness.
- Quick and long lasting results
- Non-invasive and minimal downtime

Polynucleotides differ from other skin booster injections because rather than just providing the skin with hydration, they also promote collagen and elastin. We can also inject them into several different locations on the face and body – including under the eyes, the neck and the décolletage.
What can I expect at my Polynucleotides appointment?
Prior to all injectable treatments at Revitalise Skincare Clinic we book our patients in for a personalised consultation with our Medical Practitioner. During your consultation we will discuss your skin concerns, perform a skin analysis and discuss your medical background – this allows us to ensure Polynucleotides is the most suitable treatment option for you.
During your treatment, polynucleotides will be injected into the desired areas. The procedure is generally well-tolerated, but a topical numbing cream can be applied to minimise any discomfort. All aftercare will be discussed with you to ensure optimal results.
It is extremely important to ensure the Practitioner you visit has the correct training and expertise to ensure any injectable treatment is administered safely and properly. Arvin at Revitalise Skincare Clinic has had extensive training and has years of experience in the industry, you can ensure you are in safe hands when visiting our clinic.
If you’re interested in Polynucleotides and would like to book in for a consultation at our award winning, CQC registered clinic then contact us today.
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Contact Number – 01225 760556
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